If you’ve finally decided to use dermal fillers and have settled on Juvederm, you’ve made a great choice, because Juvederm is considered a top dermal filler.  But since there are different fillers in the Juvederm family, you may be wondering which Juvederm injection is best for you. 

What is Juvederm?

Juvederm is a popular collection of dermal fillers used to rejuvenate and refresh the face.  Juvederm fillers smooth facial wrinkles and folds, replace lost volume, and plump thin lips. The collection includes Juvederm Plus XC, Juvederm Voluma XC, Juvederm Vollure XC, and Juvederm Volbella XC.   Allergan is the company behind the Juvederm fillers.

Juvederm fillers are all derived from hyaluronic acid (HA), which is a naturally occurring sugar molecule in the body that helps to keep the skin soft and moisturized. The supply of HA diminishes over time with age, and fine lines and wrinkles develop as a result. 

HA naturally binds to water molecules, so when it is injected below the skin it attracts water and this hydrates the skin, making it plumper and firmer.  HA also increases the production of collagen and this has long term rejuvenation benefits for the skin. 

Which Juvederm injection is best for you?

The Juvederm injection that’s best for you will depend on the specific concern you need addressing. 

If wrinkles, fine lines and folds are your primary concern, Juvederm has several formulations to soften these lines including the following:

Juvederm Plus XC

Smiling is good for you, but those nasolabial folds at the corner of the mouth commonly called ‘smile lines’ or ‘laugh lines,’ are not so welcome.   Nasolabial folds appear whenever you smile, but unfortunately, they tend to hang around when you’re older because of the diminished elasticity of the skin.  

That’s where Juvederm Plus XC comes in.  Juvederm Plus XC is an injectable gel that adds volume below the skin, to fill out moderate to severe wrinkles around the nose and mouth.   The results can last up to 1 year.

Juvederm Vollure XC

Juvederm Vollure XC is another solution for reducing the appearance of moderate to severe wrinkles and folds around the nose and mouth.  Juvederm Vollure is a soft filler that is easy to mold, and lasts for a long time, up to 18 months in many cases.

What makes Juvederm Vollure different from Juvederm Plus is the proprietary Vycross technology by Allergan.  Vycross Technology blends hyaluronic acid of different molecular weights to create a gel formula that is smoother, and looks and feels natural. The formulation also includes lidocaine (a local anesthetic), which helps minimize discomfort.

Wrinkles aren’t the only sign of aging; perhaps even more evident on the face is the problem of volume loss.  This is apparent in the cheeks, around the mouth, and the lips.  Juvederm fillers can also fix these issues. 

Juvederm Voluma

If you have flat cheeks and sagging skin Juvederm Voluma is the ideal solution.  The skin loses collagen support over time, causing the underlying muscles to weaken, and that’s why the cheeks appear flatter.

Juvederm Voluma is specially designed to lift the cheeks and restore facial contours.  It is the only injectable filler that is FDA cleared to correct age-related volume loss in the cheeks.  Voluma is a thick gel formula that is injected deep into the cheek area and adds volume below the surface to create well-defined cheeks.   The results of Juvederm Voluma can last up to 2 years.

Juvederm Volbella XC

If you would like fuller, plumper lips, Juvederm Volbella is the filler for you.  Volbella increases lip volume and also fills in vertical lip lines, which are commonly called “smoker’s lines.”  Despite the nickname, these lines are not usually caused by smoking but are instead the result of repetitive lip movements.  Juvederm Volbella treats these pesky wrinkles and leaves the lips fuller and more attractive.

Juvederm Voluma and Volbella are also made using Vycross technology.

Juvederm fillers are generally very safe, but some patients may have temporary side-effects such as tenderness, bruising, and swelling, at the injection sites. 


If you are in the San Francisco and Walnut Creek, CA areas, contact board certified plastic surgeon Andrew Barnett, MD for a consultation.

You can reach Dr. Barnett at www.drbarnett.com, or by calling (415) 943-0749.